Version 5.4
Mus musculus Gene: Pcdh1
Summary
InnateDB Gene IDBG-141384.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcdh1
Gene Name protocadherin 1
Synonyms 2010005A06Rik; AI585920
Species Mus musculus
Ensembl Gene ENSMUSG00000051375
Encoded Proteins
IDBP-141386
protocadherin 1
IDBP-542824
protocadherin 1
IDBP-542822
protocadherin 1
IDBP-542544
protocadherin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156453:
This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:38185915-38212053
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000057185 ENSMUSP00000055199
ENSMUST00000160721 ENSMUSP00000124732
ENSMUST00000161701 ENSMUSP00000125576
ENSMUST00000159405 ENSMUSP00000125309
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0016339 calcium-dependent cell-cell adhesion
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156453
View Gene Order
ENSBTAG00000012518
Not yet available
Cross-References
SwissProt
TrEMBL E0CXD4
UniProt Splice Variant
Entrez Gene 75599
UniGene Mm.36560 Mm.458851
RefSeq NM_029357
OMIM
CCDS CCDS29197
HPRD
IMGT
MGI ID MGI:104692
MGI Symbol Pcdh1
EMBL AC133646
GenPept
RNA Seq Atlas 75599

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca