Version 5.4
Mus musculus Gene: Gal3st1
Summary
InnateDB Gene IDBG-141423.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gal3st1
Gene Name galactose-3-O-sulfotransferase 1
Synonyms Cst; Gcst
Species Mus musculus
Ensembl Gene ENSMUSG00000049721
Encoded Proteins
IDBP-141425
galactose-3-O-sulfotransferase 1
IDBP-141427
galactose-3-O-sulfotransferase 1
IDBP-261237
galactose-3-O-sulfotransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128242:
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008]
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3\'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3\',5\'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:3983636-3999326
Strand Forward strand
Band A1
Transcripts
ENSMUST00000078757 ENSMUSP00000077815
ENSMUST00000063004 ENSMUSP00000058348
ENSMUST00000109981 ENSMUSP00000105608
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001733 galactosylceramide sulfotransferase activity
Biological Process
GO:0006682 galactosylceramide biosynthetic process
GO:0007283 spermatogenesis
GO:0009058 biosynthetic process
GO:0009247 glycolipid biosynthetic process
GO:0042552 myelination
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128242
View Gene Order
ENSBTAG00000014232
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.103414
RefSeq NM_001177691 NM_001177703 NM_016922 XM_006514756 XM_006514757
OMIM
CCDS CCDS24373
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca