Mus musculus Gene: Sec14l2
Summary
InnateDB Gene IDBG-141672.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sec14l2
Gene Name SEC14-like 2 (S. cerevisiae)
Synonyms 1300013M05Rik; Spf; TAP
Species Mus musculus
Ensembl Gene ENSMUSG00000003585
Encoded Proteins
SEC14-like 2 (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100003:
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:4097039-4123415
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000003681 ENSMUSP00000003681
ENSMUST00000132421
ENSMUST00000123901
ENSMUST00000133631
ENSMUST00000145173
ENSMUST00000136420
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008289 lipid binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006810 transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
Validated transcriptional targets of deltaNp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.253922 Mm.392514
RefSeq NM_144520 XM_006514798
OMIM
CCDS CCDS24377
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas