Version 5.4
Mus musculus Gene: Dusp22
Summary
InnateDB Gene IDBG-141692.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dusp22
Gene Name dual specificity phosphatase 22
Synonyms JKAP; JSP1; LMW-DSP2; MKPX
Species Mus musculus
Ensembl Gene ENSMUSG00000069255
Encoded Proteins
IDBP-141694
dual specificity phosphatase 22
IDBP-141696
dual specificity phosphatase 22
IDBP-260540
dual specificity phosphatase 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112679:
Gene Information
Type Protein coding
Genomic Location Chromosome 13:30659999-30711231
Strand Forward strand
Band A3.2
Transcripts
ENSMUST00000095914 ENSMUSP00000093603
ENSMUST00000091672 ENSMUSP00000089260
ENSMUST00000110310 ENSMUSP00000105939
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006470 protein dephosphorylation
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0016311 dephosphorylation
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042127 regulation of cell proliferation
GO:0046330 positive regulation of JNK cascade
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112679
View Gene Order
ENSBTAG00000027375
Not yet available
Cross-References
SwissProt Q99N11
TrEMBL
UniProt Splice Variant
Entrez Gene 105352
UniGene Mm.289646 Mm.400142
RefSeq NM_134068 NM_001037955 XM_006516519
OMIM
CCDS CCDS26417 CCDS26418
HPRD
IMGT
MGI ID MGI:1915926
MGI Symbol Dusp22
EMBL AF237619 AK149363 AL731659 BC108362
GenPept AAI08363 AAK15038 BAE28836 CAI24592 CAI24593 CAI24594
RNA Seq Atlas 105352

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca