Mus musculus Gene: Prkcsh | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-142888.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Prkcsh | ||||||||||||||||||||||
Gene Name | protein kinase C substrate 80K-H | ||||||||||||||||||||||
Synonyms | 80K-H; PKCSH | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000003402 | ||||||||||||||||||||||
Encoded Proteins |
protein kinase C substrate 80K-H
protein kinase C substrate 80K-H
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130175:
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 9:22003035-22014219 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | A3 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
Immune System pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Advanced glycosylation endproduct receptor signaling pathway
Asparagine N-linked glycosylation pathway
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
Calnexin/calreticulin cycle pathway
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KEGG |
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Advanced glycosylation endproduct receptor signaling pathway
Calnexin/calreticulin cycle pathway
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Innate Immune System pathway
Metabolism of proteins pathway
Immune System pathway
Calnexin/calreticulin cycle pathway
Immune System pathway
Asparagine N-linked glycosylation pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Advanced glycosylation endproduct receptor signaling pathway
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
Innate Immune System pathway
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KEGG |
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | |||||||||||||||||||||||
RefSeq | NM_008925 XM_006510094 XM_006510095 XM_006510096 XM_006510097 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS22918 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | |||||||||||||||||||||||
MGI Symbol | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||