InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PRKCSH

Summary

InnateDB Gene

IDBG-643543.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRKCSH

Gene Name

Glucosidase 2 subunit beta

Synonyms

VASAP-60

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008202

Encoded Proteins

IDBP-696109

Glucosidase 2 subunit beta

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130175:
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 7:17034684-17048121

Strand

Forward strand

Band

Transcripts

ENSBTAT00000010787

ENSBTAP00000010787

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001889	liver development
GO:0006491	N-glycan processing
GO:0006807	nitrogen compound metabolic process
GO:0010977	negative regulation of neuron projection development
GO:0072001	renal system development