Version 5.4
Mus musculus Gene: Dagla
Summary
InnateDB Gene IDBG-143681.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dagla
Gene Name diacylglycerol lipase, alpha
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035735
Encoded Proteins
IDBP-143683
diacylglycerol lipase, alpha
IDBP-787685
diacylglycerol lipase, alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134780:
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.[provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:10245265-10304877
Strand Reverse strand
Band A
Transcripts
ENSMUST00000039327 ENSMUSP00000046358
ENSMUST00000125567 ENSMUSP00000138702
ENSMUST00000156361
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004806 triglyceride lipase activity
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process
GO:0007405 neuroblast proliferation
GO:0019369 arachidonic acid metabolic process
GO:0022008 neurogenesis
GO:0042136 neurotransmitter biosynthetic process
GO:0046340 diacylglycerol catabolic process
GO:0071926 endocannabinoid signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000134780
View Gene Order
ENSBTAG00000013942
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_224553
Hemostasis pathway
REACT_254215
Signaling by GPCR pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_247231
Arachidonate production from DAG pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_219232
Effects of PIP2 hydrolysis pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19308
Arachidonate production from DAG pathway
REACT_2202
Effects of PIP2 hydrolysis pathway
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14797
Signaling by GPCR pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.329718
RefSeq NM_198114 XM_006527114 XM_006527115
OMIM
CCDS CCDS29574
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca