InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Shb

Summary

InnateDB Gene

IDBG-144246.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Shb

Gene Name

src homology 2 domain-containing transforming protein B

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000044813

Encoded Proteins

IDBP-144248

src homology 2 domain-containing transforming protein B

IDBP-539986

src homology 2 domain-containing transforming protein B

IDBP-533971

src homology 2 domain-containing transforming protein B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000107338:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:45423278-45532470

Strand

Reverse strand

Band

Transcripts

ENSMUST00000061986	ENSMUSP00000060433
ENSMUST00000147926
ENSMUST00000130107
ENSMUST00000125599
ENSMUST00000146236	ENSMUSP00000123176
ENSMUST00000147448	ENSMUSP00000115331

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	18 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001948	glycoprotein binding
GO:0005070	SH3/SH2 adaptor activity
GO:0005515	protein binding

Biological Process

GO:0001525	angiogenesis
GO:0001568	blood vessel development
GO:0006469	negative regulation of protein kinase activity
GO:0006915	apoptotic process
GO:0009967	positive regulation of signal transduction
GO:0030097	hemopoiesis
GO:0030154	cell differentiation
GO:0042100	B cell proliferation
GO:0045931	positive regulation of mitotic cell cycle
GO:0048514	blood vessel morphogenesis
GO:0071425	hematopoietic stem cell proliferation
GO:1900194	negative regulation of oocyte maturation