Version 5.4
Mus musculus Gene: Aldh1b1
Summary
InnateDB Gene IDBG-144536.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aldh1b1
Gene Name aldehyde dehydrogenase 1 family, member B1
Synonyms 2700007F14Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000035561
Encoded Proteins
IDBP-144538
aldehyde dehydrogenase 1 family, member B1
IDBP-624013
aldehyde dehydrogenase 1 family, member B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137124:
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:45799022-45804604
Strand Forward strand
Band B1
Transcripts
ENSMUST00000044384 ENSMUSP00000041260
ENSMUST00000172750 ENSMUSP00000134082
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006068 ethanol catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137124
View Gene Order
ENSBTAG00000020385
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00410
beta-Alanine metabolism pathway
mmu00280
Valine, leucine and isoleucine degradation pathway
mmu00340
Histidine metabolism pathway
mmu00053
Ascorbate and aldarate metabolism pathway
mmu00310
Lysine degradation pathway
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu00330
Arginine and proline metabolism pathway
mmu00380
Tryptophan metabolism pathway
mmu00040
Pentose and glucuronate interconversions pathway
mmu00620
Pyruvate metabolism pathway
mmu00561
Glycerolipid metabolism pathway
mmu00071
Fatty acid degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00340
Histidine metabolism pathway
hsa00620
Pyruvate metabolism pathway
hsa00280
Valine, leucine and isoleucine degradation pathway
hsa00330
Arginine and proline metabolism pathway
hsa00380
Tryptophan metabolism pathway
hsa00040
Pentose and glucuronate interconversions pathway
hsa00071
Fatty acid degradation pathway
hsa00310
Lysine degradation pathway
hsa00053
Ascorbate and aldarate metabolism pathway
hsa00410
beta-Alanine metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
INOH website
Tryptophan degradation pathway
INOH website
Propanoate metabolism pathway
INOH website
Arginine Proline metabolism pathway
INOH website
Pyruvate metabolism pathway
INOH website
Valine Leucine Isoleucine degradation pathway
INOH website
Lysine degradation pathway
INOH website
Histidine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL G3UYH1
UniProt Splice Variant
Entrez Gene 72535
UniGene Mm.331583
RefSeq NM_028270
OMIM
CCDS CCDS18139
HPRD
IMGT
MGI ID MGI:1919785
MGI Symbol Aldh1b1
EMBL AL772381
GenPept
RNA Seq Atlas 72535

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca