Homo sapiens Gene: ALDH1B1
Summary
InnateDB Gene IDBG-66261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALDH1B1
Gene Name aldehyde dehydrogenase 1 family, member B1
Synonyms ALDH5; ALDHX
Species Homo sapiens
Ensembl Gene ENSG00000137124
Encoded Proteins
aldehyde dehydrogenase 1 family, member B1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:38392664-38398661
Strand Forward strand
Band p13.1
Transcripts
ENST00000377698 ENSP00000366927
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004029 aldehyde dehydrogenase (NAD) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006068 ethanol catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycolysis / Gluconeogenesis pathway
Histidine metabolism pathway
Pyruvate metabolism pathway
Valine, leucine and isoleucine degradation pathway
Arginine and proline metabolism pathway
Tryptophan metabolism pathway
Pentose and glucuronate interconversions pathway
Fatty acid degradation pathway
Lysine degradation pathway
Ascorbate and aldarate metabolism pathway
beta-Alanine metabolism pathway
Glycerolipid metabolism pathway
INOH
Tryptophan degradation pathway
Propanoate metabolism pathway
Arginine Proline metabolism pathway
Pyruvate metabolism pathway
Valine Leucine Isoleucine degradation pathway
Lysine degradation pathway
Histidine degradation pathway
PID NCI
Cross-References
SwissProt P30837
TrEMBL B4DLJ0
UniProt Splice Variant
Entrez Gene 219
UniGene Hs.436219 Hs.743532
RefSeq NM_000692
HUGO HGNC:407
OMIM 100670
CCDS CCDS6615
HPRD
IMGT
EMBL AK297020 AK313344 AL135785 BC001619 BT007418 M63967
GenPept AAA96830 AAH01619 AAP36086 BAG36147 BAG59552 CAD13246
RNA Seq Atlas 219