Version 5.4
Mus musculus Gene: Ndor1
Summary
InnateDB Gene IDBG-144568.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndor1
Gene Name NADPH dependent diflavin oxidoreductase 1
Synonyms 4930447P04Rik; Ndor; NR1
Species Mus musculus
Ensembl Gene ENSMUSG00000006471
Encoded Proteins
IDBP-144570
NADPH dependent diflavin oxidoreductase 1
IDBP-251960
NADPH dependent diflavin oxidoreductase 1
IDBP-537084
NADPH dependent diflavin oxidoreductase 1
IDBP-541753
NADPH dependent diflavin oxidoreductase 1
IDBP-534811
NADPH dependent diflavin oxidoreductase 1
IDBP-534763
NADPH dependent diflavin oxidoreductase 1
IDBP-536571
NADPH dependent diflavin oxidoreductase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188566:
This gene encodes an NADPH-dependent diflavin reductase that contains both flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) binding domains. The encoded protein catalyzes the transfer of electrons from NADPH through FAD and FMN cofactors to potential redox partners. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:25244821-25256022
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000100329 ENSMUSP00000097903
ENSMUST00000114349 ENSMUSP00000109989
ENSMUST00000162680 ENSMUSP00000124985
ENSMUST00000156056
ENSMUST00000148589 ENSMUSP00000123958
ENSMUST00000129705
ENSMUST00000141808 ENSMUSP00000123247
ENSMUST00000123472
ENSMUST00000147866 ENSMUSP00000125259
ENSMUST00000132591
ENSMUST00000137355
ENSMUST00000132128 ENSMUSP00000125018
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003958 NADPH-hemoprotein reductase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
Biological Process
GO:0008219 cell death
GO:0016226 iron-sulfur cluster assembly
GO:0036245 cellular response to menadione
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0045111 intermediate filament cytoskeleton
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000188566
View Gene Order
ENSBTAG00000047061
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196637
Cytosolic iron-sulfur cluster assembly pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160176
Cytosolic iron-sulfur cluster assembly pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E0CXI9
UniProt Splice Variant
Entrez Gene 78797
UniGene Mm.40020 Mm.469232 Mm.488553
RefSeq NM_001082476 NM_001252541 NM_001252542 XM_006498443 XM_006498455
OMIM
CCDS CCDS38069 CCDS57157
HPRD
IMGT
MGI ID MGI:1926047
MGI Symbol Ndor1
EMBL AL732309
GenPept
RNA Seq Atlas 78797

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca