Version 5.4
Mus musculus Gene: Sept7
Summary
InnateDB Gene IDBG-144824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sept7
Gene Name septin 7
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000001833
Encoded Proteins
IDBP-250012
septin 7
IDBP-621943
septin 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122545:
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:25252439-25308571
Strand Forward strand
Band A4
Transcripts
ENSMUST00000115272 ENSMUSP00000110927
ENSMUST00000165594 ENSMUSP00000127641
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042802 identical protein binding
Biological Process
GO:0007049 cell cycle
GO:0007067 mitotic nuclear division
GO:0016476 regulation of embryonic cell shape
GO:0051291 protein heterooligomerization
GO:0060271 cilium morphogenesis
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005819 spindle
GO:0005886 plasma membrane
GO:0005930 axoneme
GO:0005938 cell cortex
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0016324 apical plasma membrane
GO:0030496 midbody
GO:0031105 septin complex
GO:0032154 cleavage furrow
GO:0043679 axon terminus
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000122545
View Gene Order
ENSBTAG00000001182
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.270259 Mm.415423
RefSeq NM_001205367 NM_009859 XM_006510190 XM_006510191 XM_006510193
OMIM
CCDS CCDS40565
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca