Version 5.4
Bos taurus Gene: CDC10
Summary
InnateDB Gene IDBG-633176.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDC10
Gene Name septin-7
Synonyms CDC10
Species Bos taurus
Ensembl Gene ENSBTAG00000001182
Encoded Proteins
IDBP-684869
septin-7
IDBP-684871
septin-7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122545:
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:61611420-61710127
Strand Reverse strand
Band
Transcripts
ENSBTAT00000046363 ENSBTAP00000043670
ENSBTAT00000001568 ENSBTAP00000001568
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.
Predicted by orthology
Total 49 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0042802 identical protein binding
Biological Process
GO:0007049 cell cycle
GO:0051291 protein heterooligomerization
GO:0051301 cell division
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0015629 actin cytoskeleton
GO:0015630 microtubule cytoskeleton
GO:0031105 septin complex
GO:0043679 axon terminus
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122545
View Gene Order
ENSMUSG00000001833
View Gene Order
Cross-References
SwissProt
TrEMBL F1MBT8 F1MIH2 Q6Q140 Q6Q141 Q6Q143
UniProt Splice Variant
Entrez Gene 408000
UniGene Bt.6830
RefSeq NM_001001168 XM_005205465 XM_005205466 XM_005205467 XM_005205468
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY568570 AY568572 AY568573 DAAA02010818 DAAA02010819
GenPept AAS73175 AAS73177 AAS73178
RNA Seq Atlas 408000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca