InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ykt6

Summary

InnateDB Gene

IDBG-145750.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ykt6

Gene Name

YKT6 homolog (S. Cerevisiae)

Synonyms

0610042I15Rik; 1810013M05Rik; AW105923

Species

Mus musculus

Ensembl Gene

ENSMUSG00000002741

Encoded Proteins

IDBP-145752

YKT6 homolog (S. Cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106636:
This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:5955693-5967780

Strand

Forward strand

Band

Transcripts

ENSMUST00000002818	ENSMUSP00000002818
ENSMUST00000143834

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000149	SNARE binding
GO:0005484	SNAP receptor activity
GO:0019706	protein-cysteine S-palmitoyltransferase activity

Biological Process

GO:0006810	transport
GO:0006887	exocytosis
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006903	vesicle targeting
GO:0006904	vesicle docking involved in exocytosis
GO:0006906	vesicle fusion
GO:0008152	metabolic process
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport
GO:0042147	retrograde transport, endosome to Golgi

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005768	endosome
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0031201	SNARE complex
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000106636

View Gene Order

ENSBTAG00000000274

Not yet available

Pathways

NETPATH

REACTOME

KEGG

mmu04130

SNARE interactions in vesicular transport pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa04130

SNARE interactions in vesicular transport pathway

INOH

PID NCI

Cross-References

SwissProt

Q9CQW1

TrEMBL

UniProt Splice Variant

Entrez Gene

56418

UniGene

Mm.294821 Mm.487891

RefSeq

NM_019661

OMIM

CCDS

CCDS24410

HPRD

IMGT

MGI ID

MGI:1927550

MGI Symbol

Ykt6

EMBL

AF076956 AK002916 AK007486 AK147098 AK150472 AK159253 AL645469 BC006760

GenPept

AAC26834 AAH06760 BAB22455 BAB25062 BAE27674 BAE29589 BAE34934 CAI25267

RNA Seq Atlas

56418