Version 5.4
Mus musculus Gene: Osbpl3
Summary
InnateDB Gene IDBG-146878.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Osbpl3
Gene Name oxysterol binding protein-like 3
Synonyms 1200014M06Rik; 6720421I08Rik; A530055M08; ORP3; OSBP3
Species Mus musculus
Ensembl Gene ENSMUSG00000029822
Encoded Proteins
IDBP-146880
oxysterol binding protein-like 3
IDBP-146882
oxysterol binding protein-like 3
IDBP-251698
oxysterol binding protein-like 3
IDBP-251700
oxysterol binding protein-like 3
IDBP-541243
oxysterol binding protein-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070882:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Several transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:50293330-50456201
Strand Reverse strand
Band B2.3
Transcripts
ENSMUST00000071728 ENSMUSP00000071643
ENSMUST00000090019 ENSMUSP00000087473
ENSMUST00000114468 ENSMUSP00000110112
ENSMUST00000114466 ENSMUSP00000110110
ENSMUST00000141466
ENSMUST00000133141
ENSMUST00000147621
ENSMUST00000146341 ENSMUSP00000114472
ENSMUST00000136926
ENSMUST00000154333
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0008150 biological_process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000070882
View Gene Order
ENSBTAG00000019342
Not yet available
Cross-References
SwissProt
TrEMBL D3YTT6 D3YVF7
UniProt Splice Variant
Entrez Gene 71720
UniGene Mm.400127 Mm.407503 Mm.409284 Mm.412261 Mm.472621
RefSeq NM_001163645 NM_027881 XM_006506633 XM_006506636
OMIM
CCDS CCDS39489 CCDS51771
HPRD
IMGT
MGI ID MGI:1918970
MGI Symbol Osbpl3
EMBL AC008160 AC124689
GenPept
RNA Seq Atlas 71720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca