Version 5.4
Bos taurus Gene: OSBPL3
Summary
InnateDB Gene IDBG-633670.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL3
Gene Name oxysterol-binding protein-related protein 3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019342
Encoded Proteins
IDBP-685403
oxysterol binding protein-like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070882:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Several transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:71394903-71488446
Strand Forward strand
Band
Transcripts
ENSBTAT00000025767 ENSBTAP00000025767
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006810 transport
GO:0006869 lipid transport
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0031965 nuclear membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000070882
View Gene Order
ENSMUSG00000029822
View Gene Order
Cross-References
SwissProt
TrEMBL F1MLJ5
UniProt Splice Variant
Entrez Gene 537304
UniGene Bt.18432
RefSeq NM_001192901 XM_005205541
HUGO HGNC:16370
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010991 DAAA02010992
GenPept
RNA Seq Atlas 537304

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca