InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rbmx

Summary

InnateDB Gene

IDBG-147639.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rbmx

Gene Name

RNA binding motif protein, X chromosome

Synonyms

hnRNP G

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031134

Encoded Proteins

IDBP-184725

RNA binding motif protein, X chromosome

IDBP-251149

RNA binding motif protein, X chromosome

IDBP-251151

RNA binding motif protein, X chromosome

IDBP-537924

RNA binding motif protein, X chromosome

IDBP-787819

RNA binding motif protein, X chromosome

IDBP-541275

RNA binding motif protein, X chromosome

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147274:
This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009] Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box C/D class snoRNAs are involved in site-specific 2-prime-O-ribose methylation of preribosomal RNA precursors. This snoRNA is located in an intron of the RNA binding motif protein, X-linked gene (RBMX). [provided by RefSeq, Sep 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:57383530-57393036

Strand

Reverse strand

Band

Transcripts

ENSMUST00000098470	ENSMUSP00000096070
ENSMUST00000114730	ENSMUSP00000110378
ENSMUST00000114726	ENSMUSP00000110374
ENSMUST00000140384	ENSMUSP00000125720
ENSMUST00000143310	ENSMUSP00000138198
ENSMUST00000133346	ENSMUSP00000118121

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 75 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	75 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003727	single-stranded RNA binding
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006376	mRNA splice site selection
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0045893	positive regulation of transcription, DNA-templated

Cellular Component

GO:0005634	nucleus
GO:0005681	spliceosomal complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000147274

View Gene Order

ENSBTAG00000013308

Not yet available

Pathways

NETPATH

REACTOME

REACT_249110

mRNA Splicing pathway

REACT_233572

Gene Expression pathway

REACT_260226

mRNA Splicing - Major Pathway pathway

REACT_233950

Processing of Capped Intron-Containing Pre-mRNA pathway

KEGG

mmu03040

Spliceosome pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_467

mRNA Splicing - Major Pathway pathway

REACT_125

Processing of Capped Intron-Containing Pre-mRNA pathway

REACT_1735

mRNA Splicing pathway

REACT_71

Gene Expression pathway

KEGG

hsa03040

Spliceosome pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.28275 Mm.474962

RefSeq

NM_001166623 NM_011252 XM_006527913 XM_006527914

OMIM

CCDS

CCDS30153

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas