Version 5.4
Mus musculus Gene: Cd83
Summary
InnateDB Gene IDBG-147707.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd83
Gene Name CD83 antigen
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000015396
Encoded Proteins
IDBP-147709
CD83 antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112149:
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:43785107-43803130
Strand Forward strand
Band A4
Transcripts
ENSMUST00000015540 ENSMUSP00000015540
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0014070 response to organic cyclic compound
GO:0032713 negative regulation of interleukin-4 production
GO:0032733 positive regulation of interleukin-10 production
GO:0032743 positive regulation of interleukin-2 production
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112149
View Gene Order
ENSBTAG00000031430
Not yet available
Cross-References
SwissProt O88324
TrEMBL Q3T9H6
UniProt Splice Variant
Entrez Gene 12522
UniGene Mm.57175
RefSeq NM_001289915 NM_009856
OMIM
CCDS CCDS26481
HPRD
IMGT
MGI ID MGI:1328316
MGI Symbol Cd83
EMBL AF001036 AF001037 AF001038 AF001039 AF001040 AF001041 AJ245551 AK075888 AK139410 AK154862 AK156386 AK171716 AK172396 AK172449 AK172466 AK172515 BC107344 BC107345 CH466546
GenPept AAC83185 AAC83186 AAI07345 AAI07346 BAC36032 BAE23999 BAE32886 BAE33694 BAE42629 BAE42984 BAE43011 BAE43020 BAE43044 CAB63843 EDL41001
RNA Seq Atlas 12522

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca