Version 5.4
Mus musculus Gene: Nacc2
Summary
InnateDB Gene IDBG-147801.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nacc2
Gene Name nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Synonyms 0610020I02Rik; AI448087; Btbd14a; C030048H19Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000026932
Encoded Proteins
IDBP-147803
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
IDBP-252353
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
IDBP-533432
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148411:
Gene Information
Type Protein coding
Genomic Location Chromosome 2:26055535-26123220
Strand Reverse strand
Band A3
Transcripts
ENSMUST00000028300 ENSMUSP00000028300
ENSMUST00000114159 ENSMUSP00000109796
ENSMUST00000126921
ENSMUST00000152133
ENSMUST00000128674
ENSMUST00000133212
ENSMUST00000140993 ENSMUSP00000120198
ENSMUST00000149408
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076 RNA polymerase II transcription factor binding transcription factor activity
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0008285 negative regulation of cell proliferation
GO:0010608 posttranscriptional regulation of gene expression
GO:0016575 histone deacetylation
GO:0034629 cellular protein complex localization
GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
GO:0000790 nuclear chromatin
GO:0016581 NuRD complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000148411
View Gene Order
ENSBTAG00000020490
Not yet available
Cross-References
SwissProt
TrEMBL A2ARL3
UniProt Splice Variant
Entrez Gene 67991
UniGene Mm.131074 Mm.471910
RefSeq NM_001037098 NM_026495 XM_006498259 XM_006498260
OMIM
CCDS CCDS15796
HPRD
IMGT
MGI ID MGI:1915241
MGI Symbol Nacc2
EMBL AL845455
GenPept
RNA Seq Atlas 67991

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca