Version 5.4
Homo sapiens Gene: NACC2
Summary
InnateDB Gene IDBG-92183.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NACC2
Gene Name NACC family member 2, BEN and BTB (POZ) domain containing
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148411
Encoded Proteins
IDBP-92185
NACC family member 2, BEN and BTB (POZ) domain containing
IDBP-92187
NACC family member 2, BEN and BTB (POZ) domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:136006537-136095285
Strand Reverse strand
Band q34.3
Transcripts
ENST00000371753 ENSP00000360818
ENST00000277554 ENSP00000277554
ENST00000467669
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076 RNA polymerase II transcription factor binding transcription factor activity
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0004407 histone deacetylase activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
Biological Process
GO:0006366 transcription from RNA polymerase II promoter
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0010608 posttranscriptional regulation of gene expression
GO:0016575 histone deacetylation
GO:0034629 cellular protein complex localization
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051260 protein homooligomerization
GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0016581 NuRD complex
GO:0016604 nuclear body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026932
View Gene Order
ENSBTAG00000020490
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.112895
RefSeq NM_144653
HUGO
OMIM
CCDS CCDS6993
HPRD 09831
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca