Version 5.4
Mus musculus Gene: Dtx4
Summary
InnateDB Gene IDBG-147910.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dtx4
Gene Name deltex 4 homolog (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000039982
Encoded Proteins
IDBP-147912
deltex 4 homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000110042:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:12466341-12501996
Strand Reverse strand
Band A
Transcripts
ENSMUST00000045521 ENSMUSP00000040229
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000110042
View Gene Order
Pathways
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_189085
Disease pathway
REACT_198980
IRF3 mediated activation of type 1 IFN pathway
REACT_215863
ZBP1(DAI) mediated induction of type I IFNs pathway
REACT_230745
Immune System pathway
REACT_199382
Signaling by NOTCH1 pathway
REACT_199384
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_199410
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_199405
Signaling by NOTCH1 in Cancer pathway
REACT_199407
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_199406
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_199409
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_199408
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_196447
IRF3-mediated induction of type I IFN pathway
REACT_218897
Cytosolic sensors of pathogen-associated DNA pathway
REACT_196457
STING mediated induction of host immune responses pathway
REACT_196519
Regulation of innate immune responses to cytosolic DNA pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
KEGG
mmu04330
Notch signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118811
IRF3 mediated activation of type 1 IFN pathway
REACT_118764
ZBP1(DAI) mediated induction of type I IFNs pathway
REACT_147841
STING mediated induction of host immune responses pathway
REACT_118614
Activated NOTCH1 Transmits Signal to the Nucleus pathway
REACT_163993
IRF3-mediated induction of type I IFN pathway
REACT_160082
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
REACT_160214
Signaling by NOTCH1 in Cancer pathway
REACT_6802
Innate Immune System pathway
REACT_160099
FBXW7 Mutants and NOTCH1 in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_163977
Regulation of innate immune responses to cytosolic DNA pathway
REACT_6900
Immune System pathway
REACT_160301
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
REACT_160248
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
REACT_299
Signaling by NOTCH pathway
REACT_118859
Signaling by NOTCH1 pathway
REACT_160133
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
REACT_118823
Cytosolic sensors of pathogen-associated DNA pathway
REACT_116125
Disease pathway
KEGG
hsa04330
Notch signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q6PDK8
TrEMBL
UniProt Splice Variant
Entrez Gene 207521
UniGene Mm.247695 Mm.413196
RefSeq NM_172442 XM_006526816
OMIM
CCDS CCDS29631
HPRD
IMGT
MGI ID MGI:2672905
MGI Symbol Dtx4
EMBL AK086624 BC058647 BC069975
GenPept AAH58647 AAH69975 BAC39704
RNA Seq Atlas 207521

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca