Version 5.4
Mus musculus Gene: Zfp91
Summary
InnateDB Gene IDBG-148288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp91
Gene Name zinc finger protein 91
Synonyms 9130014I08Rik; A530054C17Rik; AL024263; AW545902; Pzf; Zfp-91
Species Mus musculus
Ensembl Gene ENSMUSG00000024695
Encoded Proteins
IDBP-148292
zinc finger protein 91
IDBP-535604
zinc finger protein 91
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. The homologous human protein has been shown to function as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. A read-through transcript variant composed of Zfp91 and the downstream Cntf gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of Zfp91 and Cntf has been observed in both human and mouse. A Zfp91-related pseudogene has also been identified on chromosome 17. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:12763660-12796126
Strand Reverse strand
Band A
Transcripts
ENSMUST00000038627 ENSMUSP00000037971
ENSMUST00000142247 ENSMUSP00000124424
ENSMUST00000137256
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004842 ubiquitin-protein transferase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0070534 protein K63-linked ubiquitination
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186660
View Gene Order
ENSBTAG00000024657
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.290924 Mm.401511 Mm.439025
RefSeq NM_053009
OMIM
CCDS CCDS37927
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca