Version 5.4
Mus musculus Gene: Trmt5
Summary
InnateDB Gene IDBG-148296.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt5
Gene Name TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
Synonyms 2610027O18Rik; mKIAA1393
Species Mus musculus
Ensembl Gene ENSMUSG00000034442
Encoded Proteins
IDBP-274170
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126814:
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:73280410-73286711
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000116420 ENSMUSP00000112121
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008168 methyltransferase activity
GO:0016740 transferase activity
GO:0052906 tRNA (guanine(37)-N(1))-methyltransferase activity
Biological Process
GO:0001510 RNA methylation
GO:0008150 biological_process
GO:0009452 7-methylguanosine RNA capping
GO:0030488 tRNA methylation
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000126814
View Gene Order
ENSBTAG00000011796
Not yet available
Cross-References
SwissProt Q9D0C4
TrEMBL
UniProt Splice Variant
Entrez Gene 76357
UniGene Mm.311344
RefSeq NM_029580 XM_006516357 XM_006516358
OMIM
CCDS CCDS36474
HPRD
IMGT
MGI ID MGI:1923607
MGI Symbol Trmt5
EMBL AK011576 AK220389 BC012521
GenPept AAH12521 BAB27710 BAD90443
RNA Seq Atlas 76357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca