Version 5.4
Homo sapiens Gene: TRMT5
Summary
InnateDB Gene IDBG-8403.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRMT5
Gene Name tRNA methyltransferase 5 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000126814
Encoded Proteins
IDBP-8405
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
IDBP-583811
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
IDBP-583830
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:60971451-60981358
Strand Reverse strand
Band q23.1
Transcripts
ENST00000261249 ENSP00000261249
ENST00000553903 ENSP00000452567
ENST00000555420 ENSP00000451666
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
GO:0052906 tRNA (guanine(37)-N(1))-methyltransferase activity
Biological Process
GO:0030488 tRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034442
View Gene Order
ENSBTAG00000011796
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.380159
RefSeq NM_020810 XM_005267916
HUGO
OMIM
CCDS CCDS32092
HPRD 17213
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca