Version 5.4
Mus musculus Gene: Cdon
Summary
InnateDB Gene IDBG-148540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdon
Gene Name cell adhesion molecule-related/down-regulated by oncogenes
Synonyms Cd0; CDO; Orcam
Species Mus musculus
Ensembl Gene ENSMUSG00000038119
Encoded Proteins
IDBP-148542
cell adhesion molecule-related/down-regulated by oncogenes
IDBP-401451
cell adhesion molecule-related/down-regulated by oncogenes
IDBP-536088
cell adhesion molecule-related/down-regulated by oncogenes
IDBP-538011
cell adhesion molecule-related/down-regulated by oncogenes
IDBP-532783
cell adhesion molecule-related/down-regulated by oncogenes
IDBP-533609
cell adhesion molecule-related/down-regulated by oncogenes
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064309:
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:35421128-35507652
Strand Forward strand
Band A4
Transcripts
ENSMUST00000042842 ENSMUSP00000045547
ENSMUST00000119129 ENSMUSP00000113977
ENSMUST00000151682 ENSMUSP00000119206
ENSMUST00000137200 ENSMUSP00000116553
ENSMUST00000154652 ENSMUSP00000117499
ENSMUST00000127264 ENSMUSP00000115216
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001708 cell fate specification
GO:0001934 positive regulation of protein phosphorylation
GO:0002088 lens development in camera-type eye
GO:0007224 smoothened signaling pathway
GO:0007520 myoblast fusion
GO:0009952 anterior/posterior pattern specification
GO:0010172 embryonic body morphogenesis
GO:0014816 satellite cell differentiation
GO:0016202 regulation of striated muscle tissue development
GO:0016337 single organismal cell-cell adhesion
GO:0021987 cerebral cortex development
GO:0043410 positive regulation of MAPK cascade
GO:0043497 regulation of protein heterodimerization activity
GO:0045663 positive regulation of myoblast differentiation
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048598 embryonic morphogenesis
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051146 striated muscle cell differentiation
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:2000179 positive regulation of neural precursor cell proliferation
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000064309
View Gene Order
ENSBTAG00000009315
Not yet available
Pathways
NETPATH
REACTOME
REACT_253473
Myogenesis pathway
REACT_258600
CDO in myogenesis pathway
REACT_188576
Developmental Biology pathway
KEGG
INOH
INOH website
Hedgehog signaling pathway pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_10
Hedgehog pathway
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_21303
Myogenesis pathway
KEGG
INOH
INOH website
Hedgehog signaling pathway pathway
PID NCI
hedgehog_2pathway
Signaling events mediated by the Hedgehog family
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 57810
UniGene Mm.80509
RefSeq NM_021339 XM_006510507 XM_006510508 XM_006510509 XM_006510510 XM_006510511 XM_006510513
OMIM
CCDS CCDS22964
HPRD
IMGT
MGI ID MGI:1926387
MGI Symbol Cdon
EMBL
GenPept
RNA Seq Atlas 57810

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca