Version 5.4
Homo sapiens Gene: CDON
Summary
InnateDB Gene IDBG-75707.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDON
Gene Name Cdon homolog (mouse)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000064309
Encoded Proteins
IDBP-75709
Cdon homolog (mouse)
IDBP-245141
Cdon homolog (mouse)
IDBP-593466
Cdon homolog (mouse)
IDBP-602194
Cdon homolog (mouse)
IDBP-588561
Cdon homolog (mouse)
IDBP-601127
Cdon homolog (mouse)
IDBP-589418
Cdon homolog (mouse)
IDBP-595647
Cdon homolog (mouse)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:125955796-126063335
Strand Reverse strand
Band q24.2
Transcripts
ENST00000263577 ENSP00000263577
ENST00000392693 ENSP00000376458
ENST00000531738 ENSP00000432901
ENST00000534661 ENSP00000436755
ENST00000531830 ENSP00000432571
ENST00000525625
ENST00000531586 ENSP00000434212
ENST00000527967 ENSP00000436940
ENST00000534818 ENSP00000437176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001708 cell fate specification
GO:0001934 positive regulation of protein phosphorylation
GO:0002088 lens development in camera-type eye
GO:0007155 cell adhesion
GO:0007224 smoothened signaling pathway
GO:0007520 myoblast fusion
GO:0009952 anterior/posterior pattern specification
GO:0010172 embryonic body morphogenesis
GO:0014816 satellite cell differentiation
GO:0021987 cerebral cortex development
GO:0042692 muscle cell differentiation
GO:0043410 positive regulation of MAPK cascade
GO:0043497 regulation of protein heterodimerization activity
GO:0045664 regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048598 embryonic morphogenesis
GO:0048643 positive regulation of skeletal muscle tissue development
GO:0051057 positive regulation of small GTPase mediated signal transduction
GO:0051146 striated muscle cell differentiation
GO:0051149 positive regulation of muscle cell differentiation
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:2000179 positive regulation of neural precursor cell proliferation
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038119
View Gene Order
ENSBTAG00000009315
Not yet available
Pathways
NETPATH
NetPath_10
Hedgehog pathway
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_21303
Myogenesis pathway
KEGG
INOH
INOH website
Hedgehog signaling pathway pathway
PID NCI
hedgehog_2pathway
Signaling events mediated by the Hedgehog family
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.38034 Hs.727698
RefSeq NM_001243597 NM_016952
HUGO
OMIM
CCDS CCDS58192 CCDS8468
HPRD 16372
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca