Version 5.4
Mus musculus Gene: Msrb1
Summary
InnateDB Gene IDBG-149279.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Msrb1
Gene Name methionine sulfoxide reductase B1
Synonyms D17Wsu82e; SelR; SELX; Sepr; Sepx1
Species Mus musculus
Ensembl Gene ENSMUSG00000075705
Encoded Proteins
IDBP-149281
selenoprotein X 1
IDBP-250023
selenoprotein X 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3\' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase B (MsrB) family, and is localized in the cytosol and nucleus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:24736642-24742778
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000101800 ENSMUSP00000099300
ENSMUST00000115262 ENSMUSP00000110917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008270 zinc ion binding
GO:0033743 peptide-methionine (R)-S-oxide reductase activity
GO:0070191 methionine-R-sulfoxide reductase activity
Biological Process
GO:0006979 response to oxidative stress
GO:0030041 actin filament polymerization
GO:0030091 protein repair
GO:0045087 innate immune response
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000198736
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_013759
OMIM
CCDS CCDS28495
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca