Version 5.4
Mus musculus Gene: Sptssb
Summary
InnateDB Gene IDBG-151769.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sptssb
Gene Name serine palmitoyltransferase, small subunit B
Synonyms 1110032A04Rik; ADMP; Sssptb
Species Mus musculus
Ensembl Gene ENSMUSG00000043461
Encoded Proteins
IDBP-151771
RIKEN cDNA 1110032A04 gene
IDBP-627656
RIKEN cDNA 1110032A04 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196542:
Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:69819538-69859896
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000051239 ENSMUSP00000062794
ENSMUST00000171529 ENSMUSP00000131241
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004758 serine C-palmitoyltransferase activity
GO:0005515 protein binding
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0008150 biological_process
Cellular Component
GO:0016021 integral component of membrane
GO:0017059 serine C-palmitoyltransferase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196542
View Gene Order
ENSBTAG00000047250
Not yet available
Cross-References
SwissProt Q925E8
TrEMBL
UniProt Splice Variant
Entrez Gene 66183
UniGene Mm.45481
RefSeq NM_001164210 NM_133675
OMIM
CCDS CCDS38453
HPRD
IMGT
MGI ID MGI:1913433
MGI Symbol Sptssb
EMBL AF365876 AK004017 AK009973 AK010117 BC022628
GenPept AAH22628 AAK53702 BAC25062 BAC25279 BAC25280
RNA Seq Atlas 66183

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca