Version 5.4
Mus musculus Gene: Serpini2
Summary
InnateDB Gene IDBG-152263.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpini2
Gene Name serine (or cysteine) peptidase inhibitor, clade I, member 2
Synonyms Spi14
Species Mus musculus
Ensembl Gene ENSMUSG00000034139
Encoded Proteins
IDBP-152265
serine (or cysteine) peptidase inhibitor, clade I, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114204:
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:75242370-75270078
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000039047 ENSMUSP00000046943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030155 regulation of cell adhesion
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114204
View Gene Order
ENSBTAG00000011423
Not yet available
Cross-References
SwissProt Q9JK88
TrEMBL Q4G0D3
UniProt Splice Variant
Entrez Gene 67931
UniGene Mm.259446
RefSeq NM_026460
OMIM
CCDS CCDS17413
HPRD
IMGT
MGI ID MGI:1915181
MGI Symbol Serpini2
EMBL AF251276 AK007347 AK007510 BC098466 CH466547
GenPept AAF65821 AAH98466 BAB24976 BAB25079 EDL15478
RNA Seq Atlas 67931

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca