Version 5.4
Bos taurus Gene: SERPINI2
Summary
InnateDB Gene IDBG-636843.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINI2
Gene Name serpin I2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011423
Encoded Proteins
IDBP-688813
serpin I2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114204:
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:100791772-100827942
Strand Forward strand
Band
Transcripts
ENSBTAT00000015176 ENSBTAP00000015176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000114204
View Gene Order
ENSMUSG00000034139
View Gene Order
Cross-References
SwissProt
TrEMBL A6QPW6
UniProt Splice Variant
Entrez Gene 519219
UniGene Bt.25587
RefSeq NM_001102054
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149527 DAAA02002256 DAAA02002257
GenPept AAI49528
RNA Seq Atlas 519219

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca