InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rxfp1

Summary

InnateDB Gene

IDBG-153314.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rxfp1

Gene Name

relaxin/insulin-like family peptide receptor 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000034009

Encoded Proteins

IDBP-153316

relaxin/insulin-like family peptide receptor 1

IDBP-788194

relaxin/insulin-like family peptide receptor 1

IDBP-788195

relaxin/insulin-like family peptide receptor 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171509:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:79641611-79737880

Strand

Reverse strand

Band

Transcripts

ENSMUST00000078527	ENSMUSP00000077611
ENSMUST00000182491	ENSMUSP00000138578
ENSMUST00000183199
ENSMUST00000183040	ENSMUSP00000138152

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0042562	hormone binding
GO:0046872	metal ion binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007567	parturition
GO:0030154	cell differentiation
GO:0030198	extracellular matrix organization
GO:0060427	lung connective tissue development
GO:0060658	nipple morphogenesis