Bos taurus Gene: RXFP1
Summary
InnateDB Gene IDBG-630523.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RXFP1
Gene Name Uncharacterized protein
Synonyms RXFP2
Species Bos taurus
Ensembl Gene ENSBTAG00000010306
Encoded Proteins
relaxin/insulin-like family peptide receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171509:
This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41318286-41446129
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013620 ENSBTAP00000013620
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0042562 hormone binding
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007567 parturition
GO:0030154 cell differentiation
GO:0030198 extracellular matrix organization
GO:0060427 lung connective tissue development
GO:0060658 nipple morphogenesis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (s) signalling events pathway
Relaxin receptors pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
G alpha (s) signalling events pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Relaxin receptors pathway
Peptide ligand-binding receptors pathway
Signal Transduction pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MI30
UniProt Splice Variant
Entrez Gene 532277
UniGene
RefSeq XM_002694415 XM_610789
HUGO HGNC:19718
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02044865 DAAA02044866 DAAA02044867
GenPept
RNA Seq Atlas 532277