Mus musculus Gene: Pigz
Summary
InnateDB Gene IDBG-153427.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pigz
Gene Name phosphatidylinositol glycan anchor biosynthesis, class Z
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000045625
Encoded Proteins
phosphatidylinositol glycan anchor biosynthesis, class Z
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119227:
The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:31933851-31946046
Strand Forward strand
Band B2
Transcripts
ENSMUST00000052174 ENSMUSP00000057509
ENSMUST00000151412
ENSMUST00000134928
ENSMUST00000134666
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000026 alpha-1,2-mannosyltransferase activity
GO:0000030 mannosyltransferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0006506 GPI anchor biosynthetic process
GO:0097502 mannosylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.440388 Mm.446793
RefSeq NM_172822 XM_006522118 XM_006522119 XM_006522120
OMIM
CCDS CCDS28109
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas