Version 5.4
Mus musculus Gene: Helt
Summary
InnateDB Gene IDBG-153848.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Helt
Gene Name helt bHLH transcription factor
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000047171
Encoded Proteins
IDBP-153850
Hey-like transcription factor (zebrafish)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187821:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:46292050-46294671
Strand Reverse strand
Band B1.1
Transcripts
ENSMUST00000058636 ENSMUSP00000054823
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001967 suckling behavior
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007417 central nervous system development
GO:0009791 post-embryonic development
GO:0010259 multicellular organismal aging
GO:0010467 gene expression
GO:0021858 GABAergic neuron differentiation in basal ganglia
GO:0030182 neuron differentiation
GO:0035264 multicellular organism growth
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187821
View Gene Order
ENSBTAG00000014704
Not yet available
Cross-References
SwissProt Q7TS99
TrEMBL Q8BRJ9
UniProt Splice Variant
Entrez Gene 234219
UniGene Mm.145631
RefSeq NM_173789 XM_006509389
OMIM
CCDS CCDS22290
HPRD
IMGT
MGI ID MGI:3040955
MGI Symbol Helt
EMBL AB098077 AB120968 AK044070 BC103599 BC103600 BC103601 CH466554 DQ294234
GenPept AAI03600 AAI03601 AAI03602 ABB96784 BAC31761 BAC77659 BAD11127 EDL35571
RNA Seq Atlas 234219

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca