Version 5.4
Homo sapiens Gene: HELT
Summary
InnateDB Gene IDBG-46639.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HELT
Gene Name helt bHLH transcription factor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187821
Encoded Proteins
IDBP-46641
helt bHLH transcription factor
IDBP-482541
helt bHLH transcription factor
IDBP-481889
helt bHLH transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:185018841-185020804
Strand Forward strand
Band q35.1
Transcripts
ENST00000338875 ENSP00000343464
ENST00000505610 ENSP00000422140
ENST00000515777 ENSP00000426033
ENST00000513599
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001967 suckling behavior
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007417 central nervous system development
GO:0009791 post-embryonic development
GO:0010259 multicellular organismal aging
GO:0010467 gene expression
GO:0021858 GABAergic neuron differentiation in basal ganglia
GO:0030182 neuron differentiation
GO:0035264 multicellular organism growth
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047171
View Gene Order
ENSBTAG00000014704
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.531242
RefSeq NM_001029887 NM_001300781 NM_001300782 XM_005262989 XM_005262990
HUGO
OMIM
CCDS CCDS75214 CCDS75215
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca