Mus musculus Gene: Ascc1 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-154309.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Ascc1 | ||||||
Gene Name | activating signal cointegrator 1 complex subunit 1 | ||||||
Synonyms | 1810015P09Rik; AI550520; ASC1p50; CGI-18 | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000044475 | ||||||
Encoded Proteins |
activating signal cointegrator 1 complex subunit 1
activating signal cointegrator 1 complex subunit 1
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138303:
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 10:60002805-60099990 | ||||||
Strand | Forward strand | ||||||
Band | B4 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||
SwissProt | |||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | |||||||
UniGene | Mm.155839 Mm.486267 | ||||||
RefSeq | NM_001199187 NM_026937 XM_006514039 XM_006514040 | ||||||
OMIM | |||||||
CCDS | CCDS23870 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | |||||||
MGI Symbol | |||||||
EMBL | |||||||
GenPept | |||||||
RNA Seq Atlas | |||||||