Bos taurus Gene: ASCC1
Summary
InnateDB Gene IDBG-629948.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASCC1
Gene Name activating signal cointegrator 1 complex subunit 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000392
Encoded Proteins
activating signal cointegrator 1 complex subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138303:
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:28337349-28447014
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000504 ENSBTAP00000000504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0003723 RNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008152 metabolic process
Cellular Component
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL Q0IIJ9
UniProt Splice Variant
Entrez Gene 534915
UniGene Bt.62878
RefSeq NM_001076041
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122605 DAAA02061868
GenPept AAI22606
RNA Seq Atlas 534915