Version 5.4
Mus musculus Gene: Rab11fip3
Summary
InnateDB Gene IDBG-154473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rab11fip3
Gene Name RAB11 family interacting protein 3 (class II)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000037098
Encoded Proteins
IDBP-401419
RAB11 family interacting protein 3 (class II)
IDBP-401418
RAB11 family interacting protein 3 (class II)
IDBP-401415
RAB11 family interacting protein 3 (class II)
IDBP-539896
RAB11 family interacting protein 3 (class II)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090565:
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:25989036-26069409
Strand Reverse strand
Band A3.3
Transcripts
ENSMUST00000122103 ENSMUSP00000113521
ENSMUST00000120691 ENSMUSP00000112875
ENSMUST00000118828 ENSMUSP00000113048
ENSMUST00000144587
ENSMUST00000148021 ENSMUSP00000119626
ENSMUST00000126306
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0030306 ADP-ribosylation factor binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0000910 cytokinesis
GO:0032456 endocytic recycling
Cellular Component
GO:0005634 nucleus
GO:0005768 endosome
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0016020 membrane
GO:0030496 midbody
GO:0032154 cleavage furrow
GO:0043231 intracellular membrane-bounded organelle
GO:0045171 intercellular bridge
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000090565
View Gene Order
ENSBTAG00000016591
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
arf6downstreampathway
Arf6 downstream pathway
Cross-References
SwissProt
TrEMBL D3Z1T5
UniProt Splice Variant
Entrez Gene 215445
UniGene Mm.41191
RefSeq NM_001162868 NM_001162869 NM_153140
OMIM
CCDS CCDS50039 CCDS50040 CCDS50041
HPRD
IMGT
MGI ID MGI:2444431
MGI Symbol Rab11fip3
EMBL AC140047 AC159277
GenPept
RNA Seq Atlas 215445

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca