Mus musculus Gene: Thnsl2
Summary
InnateDB Gene IDBG-155229.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Thnsl2
Gene Name threonine synthase-like 2 (bacterial)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000054474
Encoded Proteins
threonine synthase-like 2 (bacterial)
threonine synthase-like 2 (bacterial)
threonine synthase-like 2 (bacterial)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144115:
This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:71128166-71144346
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000074241 ENSMUSP00000073861
ENSMUST00000160918 ENSMUSP00000124423
ENSMUST00000170753 ENSMUSP00000129994
ENSMUST00000170455
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
GO:0070905 serine binding
Biological Process
GO:0009071 serine family amino acid catabolic process
GO:0016311 dephosphorylation
GO:0046360 2-oxobutyrate biosynthetic process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 232078
UniGene Mm.37547 Mm.427276
RefSeq NM_001033929 NM_178413
OMIM
CCDS CCDS20225
HPRD
IMGT
MGI ID MGI:3041254
MGI Symbol Thnsl2
EMBL
GenPept
RNA Seq Atlas 232078