Homo sapiens Gene: THNSL2 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-60446.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | THNSL2 | ||||||||||||||||||
Gene Name | threonine synthase-like 2 (S. cerevisiae) | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000144115 | ||||||||||||||||||
Encoded Proteins |
threonine synthase-like 2 (S. cerevisiae)
threonine synthase-like 2 (S. cerevisiae)
threonine synthase-like 2 (S. cerevisiae)
threonine synthase-like 2 (S. cerevisiae)
threonine synthase-like 2 (S. cerevisiae)
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 2:88170295-88186636 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | p11.2 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q86YJ6 | ||||||||||||||||||
TrEMBL | C9J3J1 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 55258 | ||||||||||||||||||
UniGene | Hs.740434 | ||||||||||||||||||
RefSeq | NM_001244676 XM_005264404 XM_006712043 NM_001244678 NM_018271 XM_005264400 XM_005264401 XM_005264402 XM_006712042 XM_006712044 | ||||||||||||||||||
HUGO | HGNC:25602 | ||||||||||||||||||
OMIM | 611261 | ||||||||||||||||||
CCDS | CCDS58718 CCDS2002 CCDS74539 | ||||||||||||||||||
HPRD | 07715 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AC092836 AK001778 AK095303 BC035315 BC047758 BC064423 HM185274 | ||||||||||||||||||
GenPept | AAH35315 AAH47758 AAH64423 AAX88906 ADL14696 BAA91904 BAG53023 | ||||||||||||||||||
RNA Seq Atlas | 55258 | ||||||||||||||||||