Version 5.4
Mus musculus Gene: Impa2
Summary
InnateDB Gene IDBG-155262.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Impa2
Gene Name inositol (myo)-1(or 4)-monophosphatase 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000024525
Encoded Proteins
IDBP-155264
inositol (myo)-1(or 4)-monophosphatase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141401:
This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:67289253-67319146
Strand Forward strand
Band E1
Transcripts
ENSMUST00000025403 ENSMUSP00000025403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0052832 inositol monophosphate 3-phosphatase activity
GO:0052833 inositol monophosphate 4-phosphatase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0006021 inositol biosynthetic process
GO:0046854 phosphatidylinositol phosphorylation
GO:0046855 inositol phosphate dephosphorylation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141401
View Gene Order
ENSBTAG00000043951
Not yet available
Pathways
NETPATH
REACTOME
REACT_196478
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_188937
Metabolism pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150352
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
INOH
INOH website
Inositol phosphate metabolism pathway
PID NCI
Cross-References
SwissProt Q91UZ5
TrEMBL Q3TC14 Q3U3B7 Q924A9
UniProt Splice Variant
Entrez Gene 114663
UniGene
RefSeq NM_053261
OMIM
CCDS CCDS29320
HPRD
IMGT
MGI ID MGI:2149728
MGI Symbol Impa2
EMBL AF353730 AH010672 AK154489 AK154845 AK170962 BC011093 CH466528
GenPept AAH11093 AAK39516 AAK39517 BAE32621 BAE32871 BAE42143 EDL09656
RNA Seq Atlas 114663

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca