Version 5.4
Mus musculus Gene: Spock1
Summary
InnateDB Gene IDBG-157690.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Spock1
Gene Name sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
Synonyms Spock; testican; Ticn1
Species Mus musculus
Ensembl Gene ENSMUSG00000056222
Encoded Proteins
IDBP-623344
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
IDBP-790340
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
IDBP-790341
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
IDBP-790343
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
IDBP-790344
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152377:
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein\'s function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:57421195-57908314
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000172326 ENSMUSP00000128840
ENSMUST00000187852 ENSMUSP00000141130
ENSMUST00000189373 ENSMUSP00000139863
ENSMUST00000185502 ENSMUSP00000140409
ENSMUST00000186271 ENSMUSP00000140755
ENSMUST00000185905
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008191 metalloendopeptidase inhibitor activity
Biological Process
GO:0007165 signal transduction
GO:0010812 negative regulation of cell-substrate adhesion
GO:0010951 negative regulation of endopeptidase activity
GO:0010977 negative regulation of neuron projection development
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152377
View Gene Order
ENSBTAG00000003502
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.379020
RefSeq NM_001166463 NM_001166464 NM_001166465 NM_001166466 NM_009262
OMIM
CCDS CCDS49279
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca