Version 5.4
Mus musculus Gene: Tet1
Summary
InnateDB Gene IDBG-158224.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tet1
Gene Name tet methylcytosine dioxygenase 1
Synonyms 2510010B09Rik; AA517754; BB001228; Cxxc6; D10Ertd17e; LCX; mKIAA1676
Species Mus musculus
Ensembl Gene ENSMUSG00000047146
Encoded Proteins
IDBP-158226
tet oncogene 1
IDBP-625519
tet oncogene 1
IDBP-625522
tet oncogene 1
IDBP-625523
tet oncogene 1
IDBP-625524
tet oncogene 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138336:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:62804570-62899118
Strand Reverse strand
Band B4
Transcripts
ENSMUST00000050826 ENSMUSP00000059527
ENSMUST00000174189 ENSMUSP00000133279
ENSMUST00000174121 ENSMUSP00000134328
ENSMUST00000173905 ENSMUSP00000134571
ENSMUST00000173087 ENSMUSP00000133706
ENSMUST00000173081
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043566 structure-specific DNA binding
GO:0070579 methylcytosine dioxygenase activity
Biological Process
GO:0001826 inner cell mass cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006493 protein O-linked glycosylation
GO:0016568 chromatin modification
GO:0019827 stem cell maintenance
GO:0044030 regulation of DNA methylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0055114 oxidation-reduction process
GO:0080111 DNA demethylation
GO:0090310 negative regulation of methylation-dependent chromatin silencing
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000138336
View Gene Order
ENSBTAG00000037756
Not yet available
Pathways
NETPATH
REACTOME
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_223022
TET1,2,3 and TDG demethylate DNA pathway
REACT_233572
Gene Expression pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200682
TET1,2,3 and TDG demethylate DNA pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.17774 Mm.486810
RefSeq NM_001253857 NM_027384 XM_006513873
OMIM
CCDS CCDS48581 CCDS56706
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca