Version 5.4
Mus musculus Gene: Slc28a3
Summary
InnateDB Gene IDBG-158367.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc28a3
Gene Name solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms Cnt3
Species Mus musculus
Ensembl Gene ENSMUSG00000021553
Encoded Proteins
IDBP-158369
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
IDBP-537945
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
IDBP-533780
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197506:
Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:58545399-58610877
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000022036 ENSMUSP00000022036
ENSMUST00000140760 ENSMUSP00000123681
ENSMUST00000148396 ENSMUSP00000122865
ENSMUST00000151675
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001882 nucleoside binding
GO:0005415 nucleoside:sodium symporter activity
GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity
GO:0015390 purine-specific nucleoside:sodium symporter activity
Biological Process
GO:0006810 transport
GO:0006863 purine nucleobase transport
GO:0015855 pyrimidine nucleobase transport
GO:0015860 purine nucleoside transmembrane transport
GO:0015864 pyrimidine nucleoside transport
GO:0072531 pyrimidine-containing compound transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197506
View Gene Order
ENSBTAG00000018280
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_247934
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1206
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6VNY5
UniProt Splice Variant
Entrez Gene 114304
UniGene Mm.18188 Mm.379699 Mm.404876
RefSeq NM_022317
OMIM
CCDS CCDS26572
HPRD
IMGT
MGI ID MGI:2137361
MGI Symbol Slc28a3
EMBL AC154222 AC154454
GenPept
RNA Seq Atlas 114304

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca