Version 5.4
Mus musculus Gene: Abi2
Summary
InnateDB Gene IDBG-159322.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abi2
Gene Name abl-interactor 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026782
Encoded Proteins
IDBP-159326
abl-interactor 2
IDBP-789021
abl-interactor 2
IDBP-789023
abl-interactor 2
IDBP-789027
abl-interactor 2
IDBP-789029
abl-interactor 2
IDBP-789031
abl-interactor 2
IDBP-789033
abl-interactor 2
IDBP-789035
abl-interactor 2
IDBP-789036
abl-interactor 2
IDBP-789038
abl-interactor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138443:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:60409619-60481158
Strand Forward strand
Band C2
Transcripts
ENSMUST00000052332 ENSMUSP00000058754
ENSMUST00000188594 ENSMUSP00000140750
ENSMUST00000188618 ENSMUSP00000140274
ENSMUST00000189980 ENSMUSP00000141068
ENSMUST00000191493
ENSMUST00000189082 ENSMUSP00000140522
ENSMUST00000187709 ENSMUSP00000139867
ENSMUST00000189649
ENSMUST00000185788 ENSMUSP00000139483
ENSMUST00000187400 ENSMUSP00000139646
ENSMUST00000186097 ENSMUSP00000139501
ENSMUST00000190158 ENSMUSP00000139743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017124 SH3 domain binding
GO:0031625 ubiquitin protein ligase binding
GO:0070064 proline-rich region binding
Biological Process
GO:0007611 learning or memory
GO:0008154 actin polymerization or depolymerization
GO:0016358 dendrite development
GO:0016477 cell migration
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0043010 camera-type eye development
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005913 cell-cell adherens junction
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0030425 dendrite
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000138443
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
mmu04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160086
Regulation of actin dynamics for phagocytic cup formation pathway
REACT_12529
Signaling by VEGF pathway
REACT_6802
Innate Immune System pathway
REACT_111102
Signal Transduction pathway
REACT_6900
Immune System pathway
REACT_228166
VEGFA-VEGFR2 Pathway pathway
REACT_160123
Fcgamma receptor (FCGR) dependent phagocytosis pathway
KEGG
hsa04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
rac1_pathway
RAC1 signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001198570 NM_001198571 NM_198127 XM_006496085
OMIM
CCDS CCDS14991
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca