Version 5.4
Mus musculus Gene: Mpg
Summary
InnateDB Gene IDBG-159710.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpg
Gene Name N-methylpurine-DNA glycosylase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000020287
Encoded Proteins
IDBP-159712
N-methylpurine-DNA glycosylase
IDBP-542696
N-methylpurine-DNA glycosylase
IDBP-533083
N-methylpurine-DNA glycosylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103152:
Gene Information
Type Protein coding
Genomic Location Chromosome 11:32226505-32232700
Strand Forward strand
Band A4
Transcripts
ENSMUST00000020528 ENSMUSP00000020528
ENSMUST00000142964 ENSMUSP00000118208
ENSMUST00000144903
ENSMUST00000138050 ENSMUSP00000121960
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 69 interaction(s) predicted by orthology.
Predicted by orthology
Total 69 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003905 alkylbase DNA N-glycosylase activity
GO:0005515 protein binding
GO:0008725 DNA-3-methyladenine glycosylase activity
GO:0043916 DNA-7-methylguanine glycosylase activity
GO:0052821 DNA-7-methyladenine glycosylase activity
GO:0052822 DNA-3-methylguanine glycosylase activity
Biological Process
GO:0006284 base-excision repair
Cellular Component
GO:0005634 nucleus
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103152
View Gene Order
ENSBTAG00000026422
Not yet available
Pathways
NETPATH
REACTOME
REACT_219627
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway pathway
REACT_220827
Displacement of DNA glycosylase by APE1 pathway
REACT_231541
Resolution of AP sites via the single-nucleotide replacement pathway pathway
REACT_245705
Base Excision Repair pathway
REACT_210016
Base-Excision Repair, AP Site Formation pathway
REACT_227394
Resolution of AP sites via the multiple-nucleotide patch replacement pathway pathway
REACT_205174
Depurination pathway
REACT_233397
DNA Repair pathway
REACT_219337
Removal of DNA patch containing abasic residue pathway
REACT_205258
Cleavage of the damaged purine pathway
REACT_250836
Resolution of Abasic Sites (AP sites) pathway
REACT_205202
Recognition and association of DNA glycosylase with site containing an affected purine pathway
KEGG
mmu03410
Base excision repair pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1064
Displacement of DNA glycosylase by APE1 pathway
REACT_1357
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway pathway
REACT_933
Resolution of AP sites via the single-nucleotide replacement pathway pathway
REACT_2192
Removal of DNA patch containing abasic residue pathway
REACT_1128
Resolution of AP sites via the multiple-nucleotide patch replacement pathway pathway
REACT_2176
Recognition and association of DNA glycosylase with site containing an affected purine pathway
REACT_1729
Cleavage of the damaged purine pathway
REACT_1893
Resolution of Abasic Sites (AP sites) pathway
REACT_1104
Base Excision Repair pathway
REACT_804
Base-Excision Repair, AP Site Formation pathway
REACT_626
Depurination pathway
REACT_216
DNA Repair pathway
KEGG
hsa03410
Base excision repair pathway
INOH
PID NCI
era_genomic_pathway
Validated nuclear estrogen receptor alpha network
Cross-References
SwissProt
TrEMBL F2Z3Y1
UniProt Splice Variant
Entrez Gene 268395
UniGene Mm.263161
RefSeq NM_010822
OMIM
CCDS CCDS24520
HPRD
IMGT
MGI ID MGI:97073
MGI Symbol Mpg
EMBL AL929446
GenPept
RNA Seq Atlas 268395

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca