Version 5.4
Mus musculus Gene: Nkx3-2
Summary
InnateDB Gene IDBG-160594.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nkx3-2
Gene Name NK3 homeobox 2
Synonyms Bapx1; Nkx-3.2; NKX3.2
Species Mus musculus
Ensembl Gene ENSMUSG00000049691
Encoded Proteins
IDBP-160596
NK3 homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109705:
This gene encodes a member of the NK family of homeobox-containing proteins. The encoded protein may play a role in skeletal development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:41761483-41764501
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000060820 ENSMUSP00000051990
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007368 determination of left/right symmetry
GO:0031016 pancreas development
GO:0032331 negative regulation of chondrocyte differentiation
GO:0042474 middle ear morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0048513 organ development
GO:0048536 spleen development
GO:0048645 organ formation
GO:0048705 skeletal system morphogenesis
GO:0048706 embryonic skeletal system development
GO:0055123 digestive system development
GO:0060576 intestinal epithelial cell development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109705
View Gene Order
ENSBTAG00000010896
Not yet available
Cross-References
SwissProt P97503
TrEMBL P97938
UniProt Splice Variant
Entrez Gene 12020
UniGene Mm.2530
RefSeq NM_007524
OMIM
CCDS CCDS19259
HPRD
IMGT
MGI ID MGI:108015
MGI Symbol Nkx3-2
EMBL BC145872 BC145874 CH466524 U87957 U88716
GenPept AAB47764 AAB48514 AAI45873 AAI45875 EDL37578
RNA Seq Atlas 12020

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca