Version 5.4
Mus musculus Gene: Tagln
Summary
InnateDB Gene IDBG-160728.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tagln
Gene Name transgelin
Synonyms Sm22; Sm22a; Ws310
Species Mus musculus
Ensembl Gene ENSMUSG00000032085
Encoded Proteins
IDBP-160730
transgelin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a smooth muscle cell-specific cytoskeletal protein. The encoded protein is structurally similar to calponin, an actin-binding protein. In mouse models of atherosclerosis the gene product may be involved in plaque cell and atherosclerotic lesion formation during atherogenesis. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:45929628-45936058
Strand Reverse strand
Band A5.2
Transcripts
ENSMUST00000034590 ENSMUSP00000034590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149591
View Gene Order
ENSBTAG00000007196
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
pdgfrbpathway
PDGFR-beta signaling pathway
Cross-References
SwissProt P37804
TrEMBL
UniProt Splice Variant
Entrez Gene 21345
UniGene
RefSeq NM_011526
OMIM
CCDS CCDS23137
HPRD
IMGT
MGI ID MGI:106012
MGI Symbol Tagln
EMBL AK002880 AK077235 BC003795 L41154 L41169 L41170 U36588 Z68618
GenPept AAA79165 AAA79166 AAC52418 AAH03795 BAB22427 BAC36700 CAA92941
RNA Seq Atlas 21345

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca