Version 5.4
Bos taurus Gene: TAGLN
Summary
InnateDB Gene IDBG-630870.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAGLN
Gene Name Transgelin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007196
Encoded Proteins
IDBP-682351
Transgelin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149591:
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:28318411-28323666
Strand Forward strand
Band
Transcripts
ENSBTAT00000009469 ENSBTAP00000009469
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000149591
View Gene Order
ENSMUSG00000032085
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
pdgfrbpathway
PDGFR-beta signaling pathway
Cross-References
SwissProt Q9TS87
TrEMBL V6F957
UniProt Splice Variant
Entrez Gene 513463
UniGene
RefSeq NM_001046149 XM_005215830
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105336 GJ062397
GenPept AAI05337 DAA22376
RNA Seq Atlas 513463

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca