Version 5.4
Mus musculus Gene: Tet3
Summary
InnateDB Gene IDBG-161043.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tet3
Gene Name tet methylcytosine dioxygenase 3
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034832
Encoded Proteins
IDBP-161045
tet oncogene family member 3
IDBP-787808
tet methylcytosine dioxygenase 3
IDBP-787811
tet methylcytosine dioxygenase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187605:
Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:83362373-83459084
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000089622 ENSMUSP00000087049
ENSMUST00000056191
ENSMUST00000186548 ENSMUSP00000139630
ENSMUST00000190295 ENSMUSP00000139679
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0070579 methylcytosine dioxygenase activity
Biological Process
GO:0006493 protein O-linked glycosylation
GO:0044727 DNA demethylation of male pronucleus
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0055114 oxidation-reduction process
GO:0080111 DNA demethylation
GO:0080182 histone H3-K4 trimethylation
Cellular Component
GO:0001939 female pronucleus
GO:0001940 male pronucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187605
View Gene Order
ENSBTAG00000022381
Not yet available
Pathways
NETPATH
REACTOME
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_223022
TET1,2,3 and TDG demethylate DNA pathway
REACT_233572
Gene Expression pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200682
TET1,2,3 and TDG demethylate DNA pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8BG87
TrEMBL K9JH93 L0HN04
UniProt Splice Variant
Entrez Gene 194388
UniGene Mm.211030 Mm.421573 Mm.479194 Mm.486317
RefSeq NM_183138 XM_006505773 XM_006505774 XM_006505775 XM_006505776 XM_006505777
OMIM
CCDS CCDS51820
HPRD
IMGT
MGI ID MGI:2446229
MGI Symbol Tet3
EMBL AC090648 AC159713 AK044758 AK046543 AK046552 AK046553 BC096437 HQ423151 HQ423152 JX946278
GenPept AAH96437 ADR57137 ADR57138 AGB05430 BAC32068 BAC32779 BAC32784 BAC32785
RNA Seq Atlas 194388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca